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Mitral/Tricuspid Valvular Disease

Abstract

Recommended Article

Thirty-Day Outcomes Following Transfemoral Transseptal Transcatheter Mitral Valve Replacement: Intrepid TMVR Early Feasibility Study Results Association of Effective Regurgitation Orifice Area to Left Ventricular End-Diastolic Volume Ratio With Transcatheter Mitral Valve Repair OutcomesA Secondary Analysis of the COAPT Trial Regurgitant Volume/Left Ventricular End-Diastolic Volume Ratio: Prognostic Value in Patients With Secondary Mitral Regurgitation Italian Society of Interventional Cardiology (GIse) Registry Of Transcatheter Treatment of Mitral Valve RegurgitaTiOn (GIOTTO): Impact of Valve Disease Etiology and Residual Mitral Regurgitation after MitraClip Implantation New Evidence Supporting a Novel Conceptual Framework for Distinguishing Proportionate and Disproportionate Functional Mitral Regurgitation Pathophysiology, diagnosis and new therapeutic approaches for ischemic mitral regurgitation Patient and Hospital Characteristics of Mitral Valve Surgery in the United States Adaptive development of concomitant secondary mitral and tricuspid regurgitation after transcatheter aortic valve replacement
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Review Article2021 Jun, 77 (24) 3058–3078

JOURNAL：J Am Coll Cardiol. Article Link

Current Status and Future Prospects of Transcatheter Mitral Valve Replacement: JACC State-of-the-Art Review

A Alperi , JF Granada , M Bernier et al. Keywords: mitral regurgitation; TMVR; limitations

ABSTRACT

Mitral regurgitation (MR) is the most prevalent valvular heart disease and, when left untreated, it confers a poorer prognosis. Catheter-based repair therapies face some limitations like their applicability on challenging anatomies and the potential recurrence of significant MR over time. Transcatheter mitral valve replacement (TMVR) has emerged as a less invasive approach potentially overcoming some of the current limitations associated with transcatheter mitral valve repair. Several devices are under clinical investigation, and a growing number of systems allow for a fully percutaneous transfemoral approach. In this review, the authors aimed to delineate the main challenges faced by the TMVR field, to highlight the key aspects for procedural planning, and to describe the clinical results of the TMVR systems under clinical investigation. Finally, they also discuss what the future perspectives are for this emerging field.
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