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Shear Stress

Abstract

Recommended Article

Coronary Microcirculation in Ischemic Heart Disease Local Low Shear Stress and Endothelial Dysfunction in Patients With Nonobstructive Coronary Atherosclerosis Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium
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Original Research

JOURNAL:Circulation. Article Link

ACC19 Late Breaking Science and Simultaneous Publications

CBSMD


AMI without Cardiogenic Shock

Study Design: multicenter, prospective, randomized exploratory safety and feasibility trial, 50 patients (1:1 randomization) with anterior STEMI to LV unloading by using the Impella CP followed by immediate reperfusion (U-IR) versus delayed reperfusion after 30 minutes of unloading (U-DR).

Study Endpoints: The primary safety outcome was a composite of major adverse cardiovascular and cerebrovascular events at 30 days. Efficacy parameters included the assessment of infarct size by using cardiac magnetic resonance imaging.

Editorial - Percutaneous Support Devices for Percutaneous Coronary Intervention


AMI without Cardiogenic Shock

Study Design: multicenter, randomized, open-label trial

Study Results: Follow-up was completed for 591 of 600 patients (98.5%). Mortality was not different between the IABP and the control group (66.3% versus 67.0%; relative risk, 0.99; 95% CI, 0.88–1.11; P=0.98). There were also no differences in recurrent myocardial infarction, stroke, repeat revascularization, or rehospitalization for cardiac reasons (all P>0.05). Survivors’ quality of life as assessed by the EuroQol 5D questionnaire and the New York Heart Association class did not differ between groups.

Editorial -