Bifurcation lesions are frequently encountered, associated with greater
procedural complexity and consequently are at higher risk for restenosis
and stent thrombosis. Early trials in bifurcation percutaneous coronary
intervention favored a provisional stenting approach, but contemporary
randomized trials have highlighted potentially superior outcomes using a
double-kiss crush technique in unprotected distal left main stem
bifurcation lesions. Although the evidence is greatest for double-kiss
crush, many operators favor a mini-crush or nano-crush single-kiss
approach. In this review, the authors describe the iterations of the
crush technique and the evidence for each and review general principles
for bifurcation percutaneous coronary intervention.