Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease
De Bruyne B, Pijls NH, FAME 2 Trial Investigators et al.
KEYWORDS
fractional flow reserve; PCI; medical therapy
BACKGROUND - The preferred initial treatment for patients with stable coronary artery disease is the best available medical therapy. We hypothesized that in patients with functionally significant stenoses, as determined by measurement of fractional flow reserve (FFR), percutaneous coronary intervention (PCI) plus the best available medical therapy would be superior to the best available medical therapy alone.