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肺动脉高压

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A prediction model of simple echocardiographic variables to screen for potentially correctable shunts in adult patients with pulmonary arterial hypertension associated with atrial septal defects: a cross-sectional study Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry Refined balloon pulmonary angioplasty for inoperable patients with chronic thromboembolic pulmonary hypertension Sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A Phase IIb, randomised, double-blind, placebo-controlled study - Rationale and study design Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study Definition and Management of Segmental Pulmonary Hypertension ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association 中国肺动脉高压诊断与治疗指南（2021版） The right ventricle in pulmonary hypertension Levosimendan Improves Hemodynamics and Exercise Tolerance in PH-HFpEF: Results of the Randomized Placebo-Controlled HELP Trial
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Clinical Case Study2018 May 23. [Epub ahead of print]

JOURNAL：Int Heart J. Article Link

A Case of Pulmonary Hypertension Associated with Idiopathic Hypereosinophilic Syndrome

Ibe T, Wada H, Sakakura K et al. Keywords: Corticosteroid; Hypereosinophilia; Pulmonary arterial hypertension; Steroid therapy

ABSTRACT

Hypereosinophilic syndrome (HES) is characterized by multi-organ damage that is associated with tissue hypereosinophilia. A persistently elevated eosinophilic count is also required for the diagnosis of HES. Although HES affects various organs, damage to pulmonary artery is rarely reported. We present a case of a 39-year-old man who was diagnosed with pulmonary hypertension (PH) associated with idiopathic HES. Although the pulmonary arterial hypertension specific drugs including intravenous epoprostenol could not control his PH, corticosteroid was effective for both hypereosinophilia and PH. Our case suggests the importance of steroid therapy as well as specific drugs for pulmonary arterial hypertension in the treatment of PH associated with HES.
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