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ASCVD Prevention

Abstract

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Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies How Far We Have Come, How Far We Have Yet to Go in Atherosclerosis Research In patients with stable coronary heart disease, low-density lipoprotein-cholesterol levels < 70 mg/dL and glycosylated hemoglobin A1c < 7% are associated with lower major cardiovascular events Association of White Matter Hyperintensities and Cardiovascular Disease: The Importance of Microcirculatory Disease Association Between Depressive Symptoms and Incident Cardiovascular Diseases Initial Invasive or Conservative Strategy for Stable Coronary Disease Plaque Rupture, compared to Plaque Erosion, is associated with Higher Level of Pan-coronary Inflammation Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art Review

Review Article1999 Jan 14;340(2):115-26.

JOURNAL:N Engl J Med. Article Link

Atherosclerosis — An Inflammatory Disease

Ross R Keywords: atherosclerosis; inflammatory disease

First 100 Words

Atherosclerosis is an inflammatory disease. Because high plasma concentrations of cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the principal risk factors for atherosclerosis,1 the process of atherogenesis has been considered by many to consist largely of the accumulation of lipids within the artery wall; however, it is much more than that. Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations,2,3 cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.4,5 In fact, the lesions of atherosclerosis represent . . .