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双重抗血小板治疗持续时间

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Patient Selection and Clinical Outcomes in the STOPDAPT-2 Trial: An All-Comer Single-Center Registry During the Enrollment Period of the STOPDAPT-2 Randomized Controlled Trial 6-Month Versus 12-Month Dual-Antiplatelet Therapy Following Long Everolimus-Eluting Stent Implantation: The IVUS-XPL Randomized Clinical Trial Derivation, Validation, and Prognostic Utility of a Prediction Rule for Nonresponse to Clopidogrel: The ABCD-GENE Score Safety of six-month dual antiplatelet therapy after second-generation drug-eluting stent implantation: OPTIMA-C Randomised Clinical Trial and OCT Substudy Second-generation drug-eluting stent implantation followed by 6- versus 12-month dual antiplatelet therapy: the SECURITY randomized clinical trial Cost-Effectiveness of Different Durations of Dual-Antiplatelet Use After Percutaneous Coronary Intervention DAPT, Our Genome and Clopidogrel Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome: The TICO Randomized Clinical Trial Stopping or continuing clopidogrel 12 months after drug-eluting stent placement: the OPTIDUAL randomized trial 6- Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents in Patients Nonresistant to Aspirin Final Results of the ITALIC Trial (Is There a Life for DES After Discontinuation of Clopidogrel)

Clinical Case Study2018 May 22. [Epub ahead of print]

JOURNAL:Curr Cardiol Rev. Article Link

Rotational Atherectomy in acute STEMI with heavily calcified culprit lesion is a rule breaking solution

Shahin M. Keywords: Rotational Atherectomy ; STEMI; heavily calcified culprit lesion

ABSTRACT

Calcified coronary lesions represents technical challenges and are associated with a high frequency of restenosis and target lesion revascularization. Rotational atherectomy has been shown to increase procedural success in severely calcified lesions, facilitate stent delivery in undilatable lesions and ensure complete stent expansion. However rotational atherectomy in ST-elevation myocardial infarction (STEMI) is traditionally avoided given the concern for slow or no reflow and considerded as a contraindication by its manufacturer (Rotablator, Boston Scientific) in a lesion with a visible thrombus. This case demonstrates the successful use of rotational atherectomy to facilitate dilation and revascularization of the culprit lesion in a patient with acute anterior STEMI with ongoing chest pain and heavily calcified culprit lesion.