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Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis How Far We Have Come, How Far We Have Yet to Go in Atherosclerosis Research Can Biomarkers of Myocardial Injury Provide Complementary Information to Coronary Imaging? From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events Association of Sustained Blood Pressure Control with Multimorbidity Progression Among Older Adults Effect of Evolocumab on Complex Coronary Disease Requiring Revascularization Adenosine and adenosine receptor-mediated action in coronary microcirculation Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk: Clinical Perspectives and Basic Implications Evolocumab for Early Reduction of LDL Cholesterol Levels in Patients With Acute Coronary Syndromes (EVOPACS)

Editorial01 July 2020

JOURNAL:Eur Heart J. Article Link

Identifying coronary artery disease patients at risk for sudden and/or arrhythmic death: remaining limitations of the electrocardiogram

B Asatryan, L Roten, T Reichlin et al. Keywords: sudden death; arrhythmic death; electrocardiogram; CHD

ABSTRACT

The important study concerning the easy-to-use electrocardiogram (ECG) markers of sudden and/or arrhythmic death (SAD) in coronary artery disease (CAD) patients as presented by Chatterjee et al.1 is a weighty contribution to an intricate and still rather puzzling topic. They implicate that in CAD patients, contiguous Q waves, left ventricular hypertrophy (LVH), QRS duration, and JTc prolongation provide incremental predictive value beyond traditional risk factors for SAD. While this study is unique in providing easily measurable markers that improve SAD risk stratification, it also...