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Transcatheter Aortic Valve Replacement

科研文章

荐读文献

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation Stroke Complicating Infective Endocarditis After Transcatheter Aortic Valve Replacement Transcatheter Aortic Valve Replacement in Low-risk Patients With Bicuspid Aortic Valve Stenosis Change in Kidney Function and 2-Year Mortality After Transcatheter Aortic Valve Replacement Outcomes of procedural complications in transfemoral transcatheter aortic valve replacement Acute Aortic Syndrome Revisited: JACC State-of-the-Art Review Reduced Leaflet Motion after Transcatheter Aortic-Valve Replacement Guideline Update on Indications for Transcatheter Aortic Valve Implantation Based on the 2020 American College of Cardiology/American Heart Association Guidelines for Management of Valvular Heart Disease Late kidney injury after transcatheter aortic valve replacement From organic and inorganic phosphates to valvular and vascular calcifications

EditorialNovember 16, 2019

JOURNAL:N Engl J Med. Article Link

Timing of Intervention in Aortic Stenosis

P Lancellotti, MA Vannan. Keywords: asymptomatic patients with severe aortic stenosis; treatment timing

ABSTRACT


Current guidelines require that in patients with severe aortic stenosis, symptoms related to the valvular disease be present for consideration of transcatheter aortic-valve replacement (TAVR) or surgical aortic-valve replacement.  In the absence of symptoms, only very severe aortic stenosis is an indication (class IIa) for intervention. Kang et al. now report in the Journal the results of a trial involving patients with asymptomatic, very severe aortic stenosis who were randomly assigned to surgical aortic-valve replacement or conservative care (clinical follow-up and observation). Outcomes (death during or within 30 days after surgery [operative mortality] or death from cardiovascular causes; death from . . .