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科学研究

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无复流现象

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Pre-reading

2001年,Eeckhout和Kern将无复流现象(No-Flow Phenomenon)定义为冠状动脉循环中某一特定血管节段虽心肌灌注不足,但无机械性血管阻塞(mechanical vessel obstruction)冠状动脉造影证据。经皮冠状动脉介入治疗支架置入后在明确没有可见残余狭窄后,术者将首要关注冠状动脉血流,若发生无复流现象,或将进一步影响预后及左心室重构,增加不良心脏事件的风险。因此熟知可预防无复流现象的策略、药物(冠状动脉内注射腺苷intracoronary adenosine, 硝普钠nitropusside)和非药物(低体温法induced hypothermia)等干预法对提高介入质量、改善患者预后的重要性不言而喻。