CBS 2019
CBSMD教育中心
中 文

科学研究

Abstract

Recommended Article

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling Trial Design Principles for Patients at High Bleeding Risk Undergoing PCI: JACC Scientific Expert Panel Rationale and design of a prospective substudy of clinical endpoint adjudication processes within an investigator-reported randomised controlled trial in patients with coronary artery disease: the GLOBAL LEADERS Adjudication Sub-StudY (GLASSY) Does Risk of Premature Discontinuation of Dual-Antiplatelet Therapy Following PCI Attenuate With Increasing Age? Clinical Outcomes and Cost-Effectiveness of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease: Three-Year Follow-Up of the FAME 2 Trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Original Research

JOURNAL:CBSMD Article Link

无复流现象

CBSMD

Pre-reading

2001年,Eeckhout和Kern将无复流现象(No-Flow Phenomenon)定义为冠状动脉循环中某一特定血管节段虽心肌灌注不足,但无机械性血管阻塞(mechanical vessel obstruction)冠状动脉造影证据。经皮冠状动脉介入治疗支架置入后在明确没有可见残余狭窄后,术者将首要关注冠状动脉血流,若发生无复流现象,或将进一步影响预后及左心室重构,增加不良心脏事件的风险。因此熟知可预防无复流现象的策略、药物(冠状动脉内注射腺苷intracoronary adenosine, 硝普钠nitropusside)和非药物(低体温法induced hypothermia)等干预法对提高介入质量、改善患者预后的重要性不言而喻。