Nonculprit lesions are frequently observed in patients with ST-segment
elevation myocardial infarction. Results from recent randomized clinical
trials suggest that complete revascularization after ST-segment
elevation myocardial infarction improves outcomes. In this
state-of-the-art paper, the authors review these trials and consider how
best to determine which nonculprit lesions require revascularization
and when this should be performed.