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Prevalence of Angina Among Primary Care Patients With Coronary Artery Disease Ticagrelor versus Clopidogrel in Patients with STEMI Treated with Fibrinolytic Therapy: TREAT Trial Application of High-Sensitivity Troponin in Suspected Myocardial Infarction Early versus delayed invasive intervention in acute coronary syndromes Association of Parenteral Anticoagulation Therapy With Outcomes in Chinese Patients Undergoing Percutaneous Coronary Intervention for Non-ST-Segment Elevation Acute Coronary Syndrome Use of Mechanical Circulatory Support Devices Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock Multivessel PCI Guided by FFR or Angiography for Myocardial Infarction Coronary CT Angiography and 5-Year Risk of Myocardial Infarction Incidence, predictors, and outcomes of DAPT disruption due to non-compliance vs. bleeding after PCI: insights from the PARIS Registry Intravenous Statin Administration During Myocardial Infarction Compared With Oral Post-Infarct Administration
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Original Research2019 May 18;21(7):57.

JOURNAL：Curr Cardiol Rep. Article Link

Diagnosis and Prognosis of Coronary Artery Disease with SPECT and PET

Al Badarin FJ, Malhotra S. Keywords: Coronary artery disease; Diagnosis; Myocardial blood flow; Myocardial perfusion imaging; Prognosis

ABSTRACT

PURPOSE OF REVIEW - Radionuclide myocardial perfusion imaging (MPI) continues to be the most reliable modality for diagnosis of hemodynamically significant coronary artery disease (CAD). The application of radionuclide MPI using single photon emission computed tomography (SEPCT) and positron emission tomography (PET) for CAD is reviewed, with emphasis on diagnosis and risk stratification.


RECENT FINDINGS - Contemporary studies have reported the diagnostic and prognostic value of novel imaging protocols, employing stress-first or stress-only approach. In addition, the superior diagnostic value of PET has been established with a role of assessment of myocardial blood flow to improve risk stratification. The utility of MPI in special populations, such as the elderly, women, and diabetic patients has also been recently evaluated. Furthermore, multicenter studies have reported a similar diagnostic and prognostic value of radionuclide MPI compared with other functional and anatomical techniques for CAD. Radionuclide MPI with SPECT and PET are efficacious for diagnosis and prognosis of CAD. Its universal application in varied patient populations highlights its excellent clinical effectiveness.

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