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Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia Risk Stratification for Patients in Cardiogenic Shock After Acute Myocardial Infarction Impact of Off-Hours Versus On-Hours Primary Percutaneous Coronary Intervention on Myocardial Damage and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction Effect of Medication Co-payment Vouchers on P2Y12 Inhibitor Use and Major Adverse Cardiovascular Events Among Patients With Myocardial Infarction: The ARTEMIS Randomized Clinical Trial Effect of alirocumab on major adverse cardiovascular events according to renal function in patients with a recent acute coronary syndrome: prespecified analysis from the ODYSSEY OUTCOMES randomized clinical trial BMI, Infarct Size, and Clinical Outcomes Following Primary PCI Patient-Level Analysis From 6 Randomized Trials The (R)Evolution of the CICU - Better for the Patient, Better for Education Acute Noncardiac Organ Failure in Acute Myocardial Infarction With Cardiogenic Shock Long-term outcomes after myocardial infarction in middle-aged and older patients with congenital heart disease-a nationwide study Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Research Correspondence2018 May 14;11(9):915-917.

JOURNAL:JACC Cardiovasc Interv. Article Link

Impact of Off-Hours Versus On-Hours Primary Percutaneous Coronary Intervention on Myocardial Damage and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction

Reinstadler SJ, Stiermaier T, Eitel C et al. Keywords: off-hours; on-hours; PPCI; myocardial damage; STEMI

ABSTRACT


There is an ongoing debate on potential differences in outcome between ST-segment elevation myocardial infarction (STEMI) patients presenting outside of usual hospital working hours (“off-hours”) compared with patients presenting during classical working hours (“on-hours”) (1,2). The aim of this study was to evaluate potential differences in the amount of salvaged myocardium and the extent of myocardial damage by applying cardiac magnetic resonance (CMR) imaging in a large contemporary cohort of STEMI patients.