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动脉粥样硬化性心血管疾病预防

科研文章

荐读文献

Simple Electrocardiographic Measures Improve Sudden Arrhythmic Death Prediction in Coronary Disease Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older The Use of Sex-Specific Factors in the Assessment of Women’s Cardiovascular Risk Antithrombotic Therapy for Atherosclerotic Cardiovascular Disease Risk Mitigation in Patients With Coronary Artery Disease and Diabetes Mellitus Coronary calcification in the diagnosis of coronary artery disease Mediterranean Diet and the Association Between Air Pollution and Cardiovascular Disease Mortality Risk From Detecting the Vulnerable Plaque to Managing the Vulnerable Patient From Focal Lipid Storage to Systemic Inflammation Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis Lipid-Modifying Agents, From Statins to PCSK9 Inhibitors: JACC Focus Seminar

Review Article1999 Jan 14;340(2):115-26.

JOURNAL:N Engl J Med. Article Link

Atherosclerosis — An Inflammatory Disease

Ross R Keywords: atherosclerosis; inflammatory disease

First 100 Words

Atherosclerosis is an inflammatory disease. Because high plasma concentrations of cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the principal risk factors for atherosclerosis,1 the process of atherogenesis has been considered by many to consist largely of the accumulation of lipids within the artery wall; however, it is much more than that. Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations,2,3 cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.4,5 In fact, the lesions of atherosclerosis represent . . .