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Coronary calcification in the diagnosis of coronary artery disease Primary Prevention of Sudden Cardiac Death The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study Effect of Intravascular Ultrasound-Guided vs Angiography-Guided Everolimus-Eluting Stent Implantation: The IVUS-XPL Randomized Clinical Trial Effect of Evolocumab on Complex Coronary Disease Requiring Revascularization From Focal Lipid Storage to Systemic Inflammation Cardiovascular effects of radiation therapy Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study Clinical Risk Factors and Atherosclerotic Plaque Extent to Define Risk for Major Events in Patients Without Obstructive Coronary Artery Disease: The Long-Term Coronary Computed Tomography Angiography CONFIRM Registry Operator Experience and Outcomes After Left Main Percutaneous Coronary Intervention

Review Article1979 Jul;44(1):141-7.

JOURNAL:Am J Cardiol. Article Link

Coronary calcification in the diagnosis of coronary artery disease

Rifkin RD, Parisi AF, Folland E. Keywords: coronary artery disease; coronary calcification; atherosclerosis; diagnosis; ASCVD

ABSTRACT

Clinical, postmortem and angiographic studies of coronary calcification are reviewed to define the value of fluoroscopy in the diagnosis and management of coronary artery disease. Autopsy studies consistently show a unique association between calcification of the coronary arteries and atherosclerosis. The relation of coronary calcification to the presence of major stenosis is more variable but is strong enough to be of clinical value, particularly in the younger subject. The diagnostic value of fluoroscopy can be improved by attention to the detailed features of calcification observed with the technique. Combined use of fluoroscopy and exercise testing appears to be a valid and as yet unexploited approach to the noninvasive diagnosis of coronary stenosis. Fluoroscopy has been a neglected method of noninvasive diagnosis and is sufficiently promising to warrant greater clinical use.