PerspectiveVolume 76, Issue 13, September 2020
						JOURNAL:J Am Coll Cardiol. Article Link
					 
					
						Cardiovascular Biomarkers and Imaging in Older Adults: JACC Council Perspectives
						
							DE Forman, JA de Lemos, and for the Geriatric Cardiology Section Leadership Council.
                            							Keywords:
							aging; biomarkers; cardiovascular testing; imaging; shared decision making; stress testing                            						
					 
				 
				
					ABSTRACT
					
	Whereas the burgeoning population of older adults is intrinsically 
vulnerable to cardiovascular disease, the utility of many management 
precepts that were validated in younger adults is often unclear. Whereas
 biomarker- and imaging-based tests are a major part of cardiovascular 
disease care, basic assumptions about their use and efficacy cannot be 
simply extrapolated to many older adults. Biology, physiology, and body 
composition change with aging, with important influences on 
cardiovascular disease testing procedures and their interpretation. 
Furthermore, clinical priorities of older adults are more heterogeneous,
 potentially undercutting the utility of testing data that are 
collected. The American College of Cardiology and the National 
Institutes on Aging, in collaboration with the American Geriatrics 
Society, convened, at the American College of Cardiology Heart House, a 
2-day multidisciplinary workshop, “Diagnostic Testing in Older Adults 
with Cardiovascular Disease,” to address these issues. This review 
summarizes key concepts, clinical limitations, and important 
opportunities for research.