CBS 2019
CBSMD教育中心
中 文

Scientific Library

Abstract

Recommended Article

Derivation and Validation of a Chronic Total Coronary Occlusion Intervention Procedural Success Score From the 20,000-Patient EuroCTO Registry：The EuroCTO (CASTLE) Score Stent fracture is associated with a higher mortality in patients with type-2 diabetes treated by implantation of a second-generation drug-eluting stent Rotational atherectomy and new-generation drug-eluting stent implantation The year in cardiovascular medicine 2020: heart failure and cardiomyopathies Pediatric Post–Cardiac Arrest Care: A Scientific Statement From the American Heart Association Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure Prognostic Effect and Longitudinal Hemodynamic Assessment of Borderline Pulmonary Hypertension Effect of Systolic and Diastolic Blood Pressure on Cardiovascular Outcomes
|<<... 86 87 88 89 90 91 92 ...>>|

Original Research2019 Feb 25;12(4):335-342.

JOURNAL：JACC Cardiovasc Interv. Article Link

Derivation and Validation of a Chronic Total Coronary Occlusion Intervention Procedural Success Score From the 20,000-Patient EuroCTO Registry：The EuroCTO (CASTLE) Score

Szijgyarto Z, Rampat R, Werner GS et al. Keywords: chronic total occlusion; coronary artery disease; percutaneous coronary intervention; scoring system

ABSTRACT

OBJECTIVES - The aim was to establish a contemporary scoring system to predict the outcome of chronic total occlusion coronary angioplasty.


BACKGROUND - Interventional treatment of chronic total coronary occlusions (CTOs) is a developing subspecialty. Predictors of technical success or failure have been derived from datasets of modest size. A robust scoring tool could facilitate case selection and inform decision making.


METHODS - The study analyzed data from the EuroCTO registry. This prospective database was set up in 2008 and includes >20,000 cases submitted by CTO expert operators (>50 cases/year). Derivation (n = 14,882) and validation (n = 5,745) datasets were created to develop a risk score for predicting technical failure.


RESULTS - There were 14,882 patients in the derivation dataset (with 2,356 [15.5%] failures) and 5,745 in the validation dataset (with 703 [12.2%] failures). A total of 20.2% of cases were done retrogradely, and dissection re-entry was performed in 9.3% of cases. We identified 6 predictors of technical failure, collectively forming the CASTLE score (Coronary artery bypass graft history, Age (≥70 years), Stump anatomy [blunt or invisible], Tortuosity degree [severe or unseen], Length of occlusion [≥20 mm], and Extent of calcification [severe]). When each parameter was assigned a value of 1, technical failure was seen to increase from 8% with a CASTLE score of 0 to 1, to 35% with a score ≥4. The area under the curve (AUC) was similar in both the derivation (AUC: 0.66) and validation (AUC: 0.68) datasets.


CONCLUSIONS - The EuroCTO (CASTLE) score is derived from the largest database of CTO cases to date and offers a useful tool for predicting procedural outcome.

 

Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

>CBS CBS 2019

> CBS 2019 REGISTRATION

> CBS 2019 PROGRAM

> CBS 2019 CALL FOR SCIENCE

> CBS 2019 SPOTLIGHTS

 CBSMD

> CBSMD WEBSITE REGISTRATION

> EDUCATION CENTER

> RECOMMANDED PAPER

> TOP 10 RESEARCH PAPER

> PRE-READING

CBS 2019 CBS 2019 FACULTY Education Resource CBSMD Scientific Library
Copyright ⓒ CBS MD Nanjing China. All rights reserved. 京ICP备16025898号-11
联系我们| Top