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Transcatheter Aortic Valve Replacement

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Anticoagulation After Surgical or Transcatheter Bioprosthetic Aortic Valve Replacement Left ventricular remodelling and changes in functional measurements in patients undergoing transcatheter vs surgical aortic valve replacement: a head-to-head comparison Long-Term Outcomes of Anticoagulation for Bioprosthetic Valve Thrombosis Long-term outcome of prosthesis-patient mismatch after transcatheter aortic valve replacement von Willebrand Factor and Management of Heart Valve Disease: JACC Review Topic of the Week Impact of Pre-Existing and New-Onset Atrial Fibrillation on Outcomes After Transcatheter Aortic Valve Replacement Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic Severe Bicuspid Aortic Valve Stenosis Aortic Valve Stenosis Treatment Disparities in the Underserved JACC Council Perspectives Frailty in Older Adults Undergoing Aortic Valve Replacement: The FRAILTY-AVR Study Discrepancies in Measurement of the Thoracic Aorta: JACC Review Topic of the Week
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EditorialNovember 16, 2019

JOURNAL：N Engl J Med. Article Link

Timing of Intervention in Aortic Stenosis

P Lancellotti, MA Vannan. Keywords: asymptomatic patients with severe aortic stenosis; treatment timing

ABSTRACT

Current guidelines require that in patients with severe aortic stenosis, symptoms related to the valvular disease be present for consideration of transcatheter aortic-valve replacement (TAVR) or surgical aortic-valve replacement.  In the absence of symptoms, only very severe aortic stenosis is an indication (class IIa) for intervention. Kang et al. now report in the Journal the results of a trial involving patients with asymptomatic, very severe aortic stenosis who were randomly assigned to surgical aortic-valve replacement or conservative care (clinical follow-up and observation). Outcomes (death during or within 30 days after surgery [operative mortality] or death from cardiovascular causes; death from . . .

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