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充血性心力衰竭

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Sex- and Race-Related Differences in Characteristics and Outcomes of Hospitalizations for Heart Failure With Preserved Ejection Fraction Cardiac resynchronization therapy with a defibrillator (CRTd) in failing heart patients with type 2 diabetes mellitus and treated by glucagon-like peptide 1 receptor agonists (GLP-1 RA) therapy vs. conventional hypoglycemic drugs: arrhythmic burden, hospitalizations for heart failure, and CRTd responders rate Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study Lateral Wall Dysfunction Signals Onset of Progressive Heart Failure in Left Bundle Branch Block Lifestyle Modifications for Preventing and Treating Heart Failure Longitudinal Change in Galectin-3 and Incident Cardiovascular Outcomes A Randomized Controlled Trial to Evaluate the Safety and Efficacy of Cardiac Contractility Modulation Heart Failure With Recovered Left Ventricular Ejection Fraction: JACC Scientific Expert Panel Exercise Intolerance in Patients With Heart Failure: JACC State-of-the-Art Review Cardiac and Kidney Benefits of Empagliflozin in Heart Failure Across the Spectrum of Kidney Function: Insights From EMPEROR-Reduced
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Review ArticleVolume 7, Issue 7, July 2019

JOURNAL：JACC Heart Fail. Article Link

The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment

BA Borlaug, YNV Reddy. Keywords: heart failure; hemodynamics; pericardium

ABSTRACT

The elastic pericardium exerts a compressive contact force on the surface of the myocardium that becomes more substantial when heart volume increases, as in patients with various forms of heart failure (HF). Pericardial restraint plays an important role in determining hemodynamics and ventricular function in both health and disease. This review discusses the physiology of pericardial restraint in HF and explores the question of whether it can be targeted indirectly through medical interventions or directly through a number of existing and future therapies.

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