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充血性心力衰竭

科研文章

荐读文献

Prior Pacemaker Implantation and Clinical Outcomes in Patients With Heart Failure and Preserved Ejection Fraction Noninvasive Imaging for the Evaluation of Diastolic Function: Promises Fulfilled Differential Impact of Heart Failure With Reduced Ejection Fraction on Men and Women AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026) 2026 ESC Guidelines for the management of heart failure

Review ArticleVolume 7, Issue 7, July 2019

JOURNAL:JACC Heart Fail. Article Link

The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment

BA Borlaug, YNV Reddy. Keywords: heart failure; hemodynamics; pericardium

ABSTRACT


The elastic pericardium exerts a compressive contact force on the surface of the myocardium that becomes more substantial when heart volume increases, as in patients with various forms of heart failure (HF). Pericardial restraint plays an important role in determining hemodynamics and ventricular function in both health and disease. This review discusses the physiology of pericardial restraint in HF and explores the question of whether it can be targeted indirectly through medical interventions or directly through a number of existing and future therapies.