CBS 2019
CBSMD教育中心
English

充血性心力衰竭

科研文章

荐读文献

Unexpectedly Low Natriuretic Peptide Levels in Patients With Heart Failure Atrial Fibrillation and the Prognostic Performance of Biomarkers in Heart Failure From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease and Heart Failure (Part 2/5) Natriuretic Peptide-Guided Heart Failure Therapy After the GUIDE-IT Study Mechanical circulatory support devices for acute right ventricular failure Type 2 Diabetes Mellitus and Heart Failure: A Scientific Statement From the American Heart Association and the Heart Failure Society of America Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes Baseline Features of the VICTORIA (Vericiguat Global Study in Subjects With Heart Failure With Reduced Ejection Fraction) Trial Mechanical circulatory support devices in advanced heart failure: 2020 and beyond Age-Related Characteristics and Outcomes of Patients With Heart Failure With Preserved Ejection Fraction

Review ArticleVolume 7, Issue 7, July 2019

JOURNAL:JACC Heart Fail. Article Link

The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment

BA Borlaug, YNV Reddy. Keywords: heart failure; hemodynamics; pericardium

ABSTRACT


The elastic pericardium exerts a compressive contact force on the surface of the myocardium that becomes more substantial when heart volume increases, as in patients with various forms of heart failure (HF). Pericardial restraint plays an important role in determining hemodynamics and ventricular function in both health and disease. This review discusses the physiology of pericardial restraint in HF and explores the question of whether it can be targeted indirectly through medical interventions or directly through a number of existing and future therapies.