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充血性心力衰竭

科研文章

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Phenomapping for Novel Classification of Heart Failure With Preserved Ejection Fraction The Future of Biomarker-Guided Therapy for Heart Failure After the Guiding Evidence-Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT) Study Cardiovascular biomarkers in patients with acute decompensated heart failure randomized to sacubitril-valsartan or enalapril in the PIONEER-HF trial Circulating sST2 and catestatin levels in patients with acute worsening of heart failure: a report from the CATSTAT-HF study Frequency, predictors, and prognosis of ejection fraction improvement in heart failure: an echocardiogram-based registry study Association of Prior Left Ventricular Ejection Fraction With Clinical Outcomes in Patients With Heart Failure With Midrange Ejection Fraction Effect of Luseogliflozin on Heart Failure With Preserved Ejection Fraction in Patients With Diabetes Mellitus Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association

Review ArticleVolume 7, Issue 7, July 2019

JOURNAL:JACC Heart Fail. Article Link

The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment

BA Borlaug, YNV Reddy. Keywords: heart failure; hemodynamics; pericardium

ABSTRACT


The elastic pericardium exerts a compressive contact force on the surface of the myocardium that becomes more substantial when heart volume increases, as in patients with various forms of heart failure (HF). Pericardial restraint plays an important role in determining hemodynamics and ventricular function in both health and disease. This review discusses the physiology of pericardial restraint in HF and explores the question of whether it can be targeted indirectly through medical interventions or directly through a number of existing and future therapies.